Read firstPractice-changingGuideline / consensus

Clinical Policy: A Critical Issue Related to Direct Oral Anticoagulants in Adult Patients Presenting to the Emergency Department

Annals of Emergency Medicine1 Sept 2026Policy Statements

Read the full policy before changing a reversal pathway: the feed identifies the clinical question but does not reproduce the recommendation wording, strength or patient-specific exceptions.

EDCritix summary

This ACEP clinical policy systematically reviews agent-specific antidotes versus usual care, including prothrombin complex concentrate, for adults with acute major symptomatic bleeding while taking a direct oral anticoagulant.