Read firstPractice-changingDerivation / validation
Prospective validation of HACOR score for HFNO failure in emergency department patients with acute respiratory failure
AJEM27 Aug 2026General Emergency Medicine
Clinical takeaway
Reassess patients on HFNO at 60 minutes and use HACOR as one escalation signal. The established >5 threshold remains the reference; do not adopt the exploratory ≥8 cutoff without prospective validation.
EDCritix summary
In a prospective, unselected ED cohort, the HACOR score at 60 minutes discriminated HFNO failure substantially better than the admission score and showed no evidence of miscalibration.