Defibrillating the Data

In a prospective, unselected ED cohort, the HACOR score at 60 minutes discriminated HFNO failure substantially better than the admission score and showed no evidence of miscalibration.

This ACEP clinical policy systematically reviews agent-specific antidotes versus usual care, including prothrombin complex concentrate, for adults with acute major symptomatic bleeding while taking a direct oral anticoagulant.

Part 2 of a multidisciplinary Delphi consensus addresses the clinical-practice elements of unscheduled procedural sedation. The available feed contains only policy boilerplate, not the individual recommendations.

This updated practical guide integrates current international recommendations with two decades of operational experience, covering indications, survival windows, procedural steps, troubleshooting, human factors and team safety for emergency thoracotomy.

This item discusses whole blood versus component therapy for out-of-hospital traumatic haemorrhage and points to the 2026 NEJM trial of prehospital type O whole blood. The feed supplies a citation rather than results.

In this open-label ED RCT of 34 adults aged 65 or older with hip fracture, ultrasound-guided PENG block produced greater 30-minute pain reduction than IV morphine (median −6 versus −3 points) and no patient in the block arm required rescue analgesia.

Part 1 of the multidisciplinary consensus focuses on principles, oversight and quality monitoring for unscheduled procedural sedation. The available feed does not expose the detailed consensus statements.

EMJ's monthly evidence roundup highlights five studies, led in the feed excerpt by ORIENTAL-MeVO, a 48-centre open-label, blinded-outcome trial of thrombectomy for distal medium-vessel occlusion stroke.

A Faculty of Pre-Hospital Care consensus statement provides practical early-management recommendations for suspected crush injury after a structured evidence review and consensus process, with an explicitly UK prehospital context.

This safety letter warns clinicians and EMS leaders about potential complications from the SPEAR, a 9.5 cm 10-gauge catheter-over-needle device marketed for blind out-of-hospital chest decompression.

In a prospective multicentre cohort of 138 patients with sepsis, non-survivors started norepinephrine later than survivors; initiation within 60 minutes of hypotension was associated with lower 28-day mortality.

This shortcut review found only eight directly relevant clinical reports comparing intranasal with intramuscular adrenaline for anaphylaxis, mostly weak case-series evidence; it could not establish equivalent effectiveness.

The issue overview foregrounds the small randomised PENG-block trial for hip-fracture pain and surveys other topics relevant to emergency clinicians, trainees, nurses and the public.

This critical appraisal reviews the AUGMENT-VA randomised trial: manual pressure augmentation lowered transthoracic impedance during defibrillation but did not improve survival to hospital discharge.

This procedural review describes ultrasound-guided common femoral arterial access, Seldinger sheath insertion, competency development and pitfalls as endovascular resuscitation and ECPR expand.

In their response, the authors reiterate findings from more than 5.3 million encounters at 21 community EDs: over one-third of the sickest patients were undertriaged, with a median eight-minute delay versus correctly identified high-acuity patients.

This ACEP Now report summarises the PECARN PRoMPT BOLUS trial comparing normal saline with balanced crystalloid in children with suspected septic shock; the report characterises both strategies as safe and effective.

This international-journal digest republishes editor-selected abstracts from several emergency medicine societies, including a randomised trial of intranasal versus subcutaneous ketamine for acute traumatic pain.

This ECG letter argues that apparent pauses were caused by intermittent recording failure rather than vagal stimulation, citing baseline movement and a deformed T wave without a preceding recorded QRS complex.

This letter highlights methodological limitations that may complicate interpretation of a negative dose-response trial of bupivacaine sphenopalatine ganglion block for ED headache.